Glycosylation (adding simple carbohydrates) can improve the properties of small molecules in many ways.
It can increase solubility, improve absorption, enhance blood-brain-barrier uptake, change metabolism, alter receptor binding, improve taste, refresh or improve your IP, and much more. All this from just adding sugar!
The term “sugar” covers a wide variety of molecules – glucose, galactose, rhamnose, sialic acid, glucuronic acid, GlcNAc and many more. Each confers different properties when added to a molecule. Adding one sugar on another can further improve your compound.
River Stone is a world-leader in the enzymatic glycosylation of small molecules. We offer advice on what glycosylation can (and cannot) do for you.