Advantages of Glycosylation:

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• Improve Solubility - Curcumin solubility improved 230x with one glucose unit added. And 22 million times with six glucose units

• Optimise Drug Delivery – Glucosylated Vitamin E diffuses through the skin and is then metabolized to the active form

• Improve BBB Penetration – Glucosylated endorphins are 2x better taken up in the brain, with better analgesic effects

• Optimise Tissue Targeting – 60% of oral glucosylated dexamethasone reaches the lower bowel, vs 1% of non-glucosylated.  It is then cleaved to the active form

• Improve Activity – morphine-6-glucuronide is a 45-60x more potent analgesic than morphine in animal models, with a longer lasting effect

• Modify organoleptic properties – Rebaudioside M works better as a sweetener than all other rebaudiosides tested

• Create novel molecules – with potentially novel utilities and refreshed IP

• Improve scalability of production

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See examples of glycosylation in our applications

Glycosylation in Food Applications 

Improve Activity via Glycosylation

Improve BBB Penetration via Glycosylation 

Improve Production via Glycosylation 

Improve Solubility via Glycosylation 

Improving Taste via Glycosylation 

Glycosylation for Pharma Applications 

Reduction of Toxicity via Glycosylation